Hey Matt B ... How the hell o are you ??? :)

2nd Light Forums
Decrease font size
Increase font size
Topic Title: ECMO Saving Lives of COVID-19 Patients
Topic Summary: Extracorporeal Membrane Oxygenation
Created On: 04/15/2020 01:57 PM
Linear : Threading : Single : Branch
Topic Tools Topic Tools
View topic in raw text format. Print this topic.
 04/15/2020 01:57 PM
User is offline View Users Profile Print this message


RegularJoe

Posts: 3679
Joined Forum: 11/20/2011

1 in Phoenix:
https://www.azcentral.com/stor...-treatment/2991613001/

2 in Seattle:
https://news.yahoo.com/emergen...r-death-054816082.html

I was thinking last week it would be nice if something like that existed. Obviously it has already been invented and tested. Glad to see docs trying more out-of-the-box stuff.

Sounds a bit complicated and risky, as well as the machines and expertise being few and far between. I wonder if a dialysis machine could be modified to do something similar (oxygenation, pH compensation, etc.)

Edit: Added diagram


Edited: 04/16/2020 at 06:08 PM by RegularJoe
 04/15/2020 03:59 PM
User is offline View Users Profile Print this message


Cole

Posts: 68362
Joined Forum: 07/22/2003

NPR did a story on the doctor that survived due to the machine. He said he was 100% sure that it was the machine that saved his life. Unfortunately, the machines are rare.

I agree, out of the box is good.

-------------------------
I was right.

Edited: 04/15/2020 at 04:01 PM by Cole
 04/16/2020 11:52 AM
User is offline View Users Profile Print this message


Sharktower

Posts: 2042
Joined Forum: 03/19/2004

Just a clarification here. ECMO is neither experimental nor rare. In fact, your town likely has ECMO capabilities at one of the larger hospitals. Also, ECMO does not save a life. It is known as a bridging treatment. The simple explanation is that it is a way to take blood and bypass the heart and/or the lungs. A machine outside the body (that's the extra-corporeal part) will do the gas exchange and pumping that your lungs and heart do, respectively. For otherwise healthy people with a bad COVID infection, it is not a bad last ditch effort as you can remain on ECMO until your immune system gets the virus under control and your lungs improve. Very cool stuff.

-------------------------

we are they, they are us -- Thich Nhat Hanh

 04/16/2020 12:16 PM
User is offline View Users Profile Print this message


RustyTruck

Posts: 33375
Joined Forum: 08/02/2004

Yeah ECMO has been around a long time. It's typically a last resort.

-------------------------
Capitalism is based on the ridiculous notion that you can enjoy limitless growth in a closed, finite system.

In biology, such behavior of cells is called "cancer".
 04/16/2020 05:57 PM
User is offline View Users Profile Print this message


RegularJoe

Posts: 3679
Joined Forum: 11/20/2011

Another success story on 29-week pregnant Ohio woman

SharkTower, I appreciate the time you've taken to inject doses of reality here. I know a few local ER people, and I wouldn't trade jobs with them in the best of times! Thank you, and best of luck to you in dealing with this pandemic.

My basis for the "few and far between" comment was from the Phoenix article:

Will ECMO be used more widely?

ECMO has been used for H1N1, flu and lung injury patients for many years, Ovil said. But it's a resource- and labor-intensive treatment and also a scarce resource.

For approximately every 50 to 100 ventilators, there is just one ECMO machine available, Riley said. HonorHealth has five in its system. If the treatment continues to prove successful for other critical COVID-19 patients, there may not be enough devices to help all the patients in need.

Most patients with COVID-19 can be supported with a ventilator, but a subset of them get so ill that a ventilator no longer helps. ECMO could be most useful for that type of patient, Ovil said.

The Food and Drug Administration last week issued guidance to expand the availability of ECMO devices to help address COVID-19.


Link to FDA 1-page letter

Link to FDA's 13-page PDF

I later saw these:

Article from Ireland:

If life-saving ECMO machine is available for Boris Johnson then why not for Brian or Betty from Belfast?

A life-saving oxygen machine will be available for British PM Boris Johnson if he becomes critically ill from coronavirus but the same ECMO machine is not an option for anyone in Belfast.

That's the shock claim by a South Belfast doctor Micheal Donnelly who has called for life-saving ECMO machines to be bought for local hospitals on the coronavirus frontline.

<...>

"Health Minister Robin Swann has refused to purchase an extracorporeal membrane oxygenation machine (ECMO) for use here, suggesting critically-ill patients will be flown to Newcastle, England, to access equipment there," says Dr Donnelly.

"But that's just not going to happen. It would be reckless in the extreme for nursing staff to take a highly-infectious patient on an airplane and fly them an hour to Newcastle. And, by the time they got there, the patient would be dead."


A BBC article included this about the hospital where Boris Johnson was treated:

St Thomas' Hospital has experience in treating coronavirus patients in its ICU. For extremely serious cases it can use a life support machine called ECMO (extracorporeal membrane oxygenation) which replaces some of the function of the heart and lungs.

There are only a handful of these machines around the country.


Is that (50:1 or 100:1) number realistic, outdated, or more likely in rural/suburban areas? Surprising for an area like Belfast?


Is the ECMO use simpler and less risky if the heart is healthy and only the lungs need to be bypassed?

According to UCSF

There are two types of ECMO. The VA ECMO is connected to both a vein and an artery and is used when there are problems with both the heart and lungs.

The VV ECMO is connected to one or more veins, usually near the heart, and is used when the problem is only in the lungs.

USCF is also now using a smaller portable ECMO device that is light enough to be carried by one person and can be transported in an ambulance or helicopter, making it possible to provide ECMO relief in emergency cases.


Are VV ECMO and VA ECMO typically done with the same machine in different modes, or are they typically distinctly separate machines?

Is there any way a dialysis machine could be modified to do the oxygenation function, in the absence of a real ECMO, and might that buy patients time until a true ECMO machine becomes available?
 04/17/2020 07:29 AM
User is offline View Users Profile Print this message


Sharktower

Posts: 2042
Joined Forum: 03/19/2004

Dude, really good questions. Excuse my laziness, but I didn't read the articles. But let me give some answers. Not sure where the 50:1 comes from, but ECMO is definitely a very limited resource, enough that many hospitals have to transport patients out for it. Some areas just don't have it at all. Because patients who need it are so sick, sometimes it's just not even feasible to transport them to an ECMO center. And yes, ECMO is much safer and effective in patients who don't have lots of underlying health problems. Picking the right candidate is what makes ECMO so tricky. The 80yr old nursing home patient with every chronic problem currently undergoing CPR is unlikely to benefit. On the other hand, the young healthy woman with a big blood clot in the heart might be a good candidate for ECMO while they fish out the goober in her lungs. Not to go off on a tangent, but the above points to the reality of "healthcare rationing" that is a hot-button term in the media. The truth is that things like ECMO require a specialized team, lots of equipment, big catheters shoved in big blood vessels---all this means risk to the team and the patient, occupying precious equipment and highly trained personnel. It's a super delicate balance that is much more complex than the "picking who lives and who dies" version we hear about in the media. Regarding your question about VA and VV ECMO, the equipment is getting better all the time and it is my understanding that standard setups can do both. It's really just about where you place the catheters. Lastly, another great question about the use of a hemodialysis machine to oxygenate the blood. Coincidentally, a nephrologist mentioned something like this the other day, but I have not heard of anything like that before. It's easy to nerd out on this stuff because it is the latest and greatest in high tech CPR and a relatively new frontier even for people in medicine. EDIT: tried multiple times to make paragraphs but it won't let me. sorry

-------------------------

we are they, they are us -- Thich Nhat Hanh



Edited: 04/17/2020 at 07:31 AM by Sharktower
Statistics
146495 users are registered to the 2nd Light Forums forum.
There are currently 1 users logged in to the forum.

FuseTalk Basic Edition - © 1999-2024 FuseTalk Inc. All rights reserved.

First there was Air Jordan .