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Topic Title: Not good Topic Summary: Created On: 07/13/2020 12:40 PM |
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07/13/2020 12:40 PM
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This is awaiting peer review and on an early release server. The methodology seems solid.
Not good at all A few key points. This: Using sequential serum samples collected up to 94 days post onset of symptoms (POS) from 65 RT-qPCR confirmed SARS-CoV-2-infected individuals, we show seroconversion in >95% of cases and neutralizing antibody (nAb) responses when sampled beyond 8 days POS. We demonstrate that the magnitude of the nAb response is dependent upon the disease severity, but this does not affect the kinetics of the nAb response. Declining nAb titres were observed during the follow up period. Whilst some individuals with high peak ID50 (>10,000) maintained titres >1,000 at >60 days POS, some with lower peak ID50 had titres approaching baseline within the follow up period. A similar decline in nAb titres was also observed in a cohort of seropositive healthcare workers from Guy's and St Thomas' Hospitals. We suggest that this transient nAb response is a feature shared by both a SARS-CoV-2 infection that causes low disease severity and the circulating seasonal coronaviruses that are associated with common colds. This study has important implications when considering widespread serological testing, Ab protection against re-infection with SARS-CoV-2 and the durability of vaccine protection. And this: In summary, using sequential samples from SARS-CoV-2 infected individuals collected up to 94 days POS, we demonstrate declining nAb titres in the majority of individuals. For those with a low nAb response, titres can return to base line over a relatively short period. |
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07/13/2020 12:47 PM
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In layman's terms that means ????
------------------------- If I should ever die, God forbid, let this be my epitaph: THE ONLY PROOF HE NEEDED FOR THE EXISTENCE OF GOD WAS MUSIC - KV |
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07/13/2020 12:51 PM
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Sobering.
Options and likelihoods of success: Vaccine administered to everyone as often as it takes until the virus is gone. Low Somehow work as a world to stomp this out. Low Continued $hitstorm until breakthrough. High Above is from a noob's perspective (me). Below is comment on the link: "In any infection IgM responses converting to IgG responses fall over time and rise when there is a secondary antigen exposure. Why do these findings suggest that there is loss of immunity with declining neutralising antibody levels? Surely the questions are: what happens after secondary antigen exposure? Do the neutralising antibody levels rise again? Do they protect from developing the same clinical disease again? Do they affect severity of disease after second exposure?" So that's more like it. Edited: 07/13/2020 at 12:56 PM by Greensleeves |
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07/13/2020 01:00 PM
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In short these 2 things:
1. Antibody levels correspond to disease severity. 2. Antibody levels decreased significantly over the testing period (basically 3 months) regardless of disease severity. |
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07/13/2020 01:15 PM
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A quarter of the 'common cold' cases are in fact caused by lesser coronaviruses and immunity only lasts 3-4 months on average. This study seems to confirm that this is also true for Covid-19. This has huge implications on vaccines.
@Greenie - good post |
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07/13/2020 01:19 PM
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------------------------- I :heart; Q |
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07/13/2020 01:27 PM
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Same thing as always when a prog reports something - we're doomed. Progs seem to be a doomsday cult of some sort. Of course, if they were ever to take over, we would be doomed. A smarter person would look at how this research might affect vaccines and things actually being able to return to normal instead of blathering on about nonsense. |
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07/13/2020 01:34 PM
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TrumPatsy has lost his chops and with that went through a transmutation into a Putin Trollbot.
I quit paying attention to (and defending) him a couple years ago when he made some really stupid comments about our military. Plus, his "I love Putin" bromance is weird. So, make no assumption about his sincerity or critical thinking skills. He is simply a troll now. ------------------------- If I should ever die, God forbid, let this be my epitaph: THE ONLY PROOF HE NEEDED FOR THE EXISTENCE OF GOD WAS MUSIC - KV Edited: 07/13/2020 at 01:34 PM by Bamboo |
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07/13/2020 01:37 PM
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------------------------- I :heart; Q |
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07/13/2020 01:46 PM
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What pigblo brings to the table......lol.
ruh-roh...... ------------------------- It's a democratic hoax Edited: 07/13/2020 at 01:51 PM by nukeh2o |
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07/13/2020 02:05 PM
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For those who are not adverse to good news, several treatments are in phase 3 testing and are looking promising. In any case, the study referenced by Riddle Me would indicate that lock downs and such are pointless. Makes no sense to destroy the economy for something that everyone will eventually get and will hang around forever.
------------------------- I :heart; Q |
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07/13/2020 02:14 PM
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For those who are not adverse to good news, several treatments are in phase 3 testing and are looking promising. In any case, the study referenced by Riddle Me would indicate that lock downs and such are pointless. Makes no sense to destroy the economy for something that everyone will eventually get and will hang around forever. Weeee-weee!, sez Dr. walter "pigblo" mitty. Please remind us of your pandemic epidemiology credentials again, professor.... Batting 1 in one hundred so far, raftboy....... ------------------------- It's a democratic hoax |
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07/13/2020 02:17 PM
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For those who are not adverse to good news, several treatments are in phase 3 testing and are looking promising. In any case, the study referenced by Riddle Me would indicate that lock downs and such are pointless. Makes no sense to destroy the economy for something that everyone will eventually get and will hang around forever. IT'S OVER! ------------------------- When America was "great" |
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07/13/2020 02:53 PM
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...you're over!
Fool! ------------------------- The REAL truth is....both of the forum idiots are OWNED. -BOTH of them have no clue who their owner is. -They are both card carrying narcissists. ^These are PROVED facts. |
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07/13/2020 03:00 PM
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OK Dr. YouTube hahaha Got any more YouTube miracle cures to hock? L O L ------------------------- When America was "great" Edited: 07/13/2020 at 03:01 PM by fishkller |
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07/13/2020 03:04 PM
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OK Dr. YouTube hahaha Got any more YouTube miracle cures to hock? L O L ^^^^Claims to have me on ignore. He's a liar! A pathological liar in fact. One of mt BIGgest fans! ------------------------- The REAL truth is....both of the forum idiots are OWNED. -BOTH of them have no clue who their owner is. -They are both card carrying narcissists. ^These are PROVED facts. |
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07/13/2020 03:27 PM
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Eel Enema boy spews more nonsense.
Turns out that purple dildo he sports :is actually a powerful emitter of virus killing uv and x-rays! That and a gallon of Alex jones unpatented, unregulated zinc "miracle cure" herbicide, fungicide, algaecide, pesticide a day! And he still be a clueless inbred laaa-HOOO-zer....with diseases. Also bleaches sidewalks, driveways. Spray it on the lawn! No bugs, no weeds...no grass! MIRACLE CURE! duuhhuuuhhuuuhhhhhhh......... ------------------------- It's a democratic hoax |
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07/13/2020 04:33 PM
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OK Dr. YouTube hahaha Got any more YouTube miracle cures to hock? L O L More like a Nurse Memesy. |
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07/13/2020 04:37 PM
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Tfap is getting to blocking state. He offers nothing but bullshit.
FK 2.0 for sure. ------------------------- I was right. |
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07/13/2020 05:33 PM
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Tfap is getting to blocking state. He offers nothing but bullshit. FK 2.0 for sure. Then Coleslaw will have absolutely no one to disagree with! Only those that share his seriously fucked up traitorous prog commie demoshit agenda! He can have one BIG circle-jerk! ------------------------- The REAL truth is....both of the forum idiots are OWNED. -BOTH of them have no clue who their owner is. -They are both card carrying narcissists. ^These are PROVED facts. Edited: 07/13/2020 at 05:34 PM by Fish Killer |
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